nanoFRET
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nanoFRET
Niko HILDEBRANDT (PhD, Professor)
McMaster University - Faculty of Engineering
Engineering Physics
Hamilton, ON L8S 4K1 - CANADA
hildebrandt@mcmaster.ca
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Multiplexed luminescence biosensing
nanoFRET is a young interdisciplinary team comprised of chemists,
physicists, and biochemists who are joining their expertises to create
and develop novel biosensing technologies and integrate these into
real-life bioapplications in cooperation with other academic groups
and industrial partners. Our main focus is the application of Förster
Resonance Energy Transfer (FRET) with lanthanide complexes, lanthanide
nanoparticles, quantum dot nanocrystals, and organic dyes. Using
time-resolved optical spectroscopy and imaging technologies, we fully
exploit the unique advantages of these luminescent markers for
ultra-sensitive multiplexed detection, e.g., for in vitro diagnostics
or live cell investigations.
KEYWORDS:
FRET, biosensing, diagnostics, biomarkers, quantum dots, terbium,
upconversion, time-resolved, multiplexing, spectroscopy, imaging,
DNA, RNA, antibodies